Anti-arthritis activity of cationic materials

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Anti-arthritis activity of cationic materials

Cationic materials exhibit remarkable anti-inflammatory activity in experimental arthritis models. Our aim was to confirm this character of cationic materials and investigate its possible mechanism. Adjuvant-induced arthritis (AIA) models were used to test cationic materials for their anti-inflammatory activity. Cationic dextran (C-dextran) with different cationic degrees was used to investigat...

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C ATIONIC PROTEINS are important constituents of polymorphonuclear ( PMN ) leukocyte lysosomes. These proteins are rich in arginine and lysine. This accounts for their strong electro-positivity.13 These proteins are without apparent enzyme activity; nevertheless they possess a variety of biological activities.1’4#{176} We have recently described an anticoagulant activity of these proteins that ...

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The Anti-Inflammatory Activity of Toonaciliatin K against Adjuvant Arthritis

Toonaciliatin K is a natural limonoid purified from the Toona ciliata Roem. var. ciliata (Meliaceae). This study is to reveal the inflammatory suppression effect of toonaciliatin K and further the intrinsic mechanism. Firstly, anti-inflammatory effect of toonaciliatin K was evaluated in lipopolysaccharide- (LPS-) induced RAW264.7 cells. RT-PCR results indicated that the mRNA expressions of TNF-...

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Antibacterial Activity of Cationic Proteins

A B S T R A, C T Human granulocytes contain several cationic proteins with a molecular weight of approximately 25,000, almost identical amino acid composition, and complete immunologic identity. These proteins possess a chymotrypsin-like protease activity at a neutral pH. The antibacterial activity of the cationic proteins has been studied. Bactericidal activities are found against both Gram-po...

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anti-arthritic activity of premna serratifolia linn., wood against adjuvant induced arthritis

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ژورنال

عنوان ژورنال: Journal of Cellular and Molecular Medicine

سال: 2010

ISSN: 1582-1838

DOI: 10.1111/j.1582-4934.2009.00806.x